Associate Professor
Department of
Chemistry
Patents:-
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Cyclic Ester Ring-Opened Oligomers and Met hods of
Preparation. Richard A. Gross, Kirpal S. Bisht, David L. Kaplan, Graham Swift
and Fang Deng. US Patent Patent # 5,981,743 issued |
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Treatment of Cancer with
Chemically-modifi ed Sophorolipids. Richard A.
Gross, Kirpal S. Bisht, Carmen Scholz, Sashi Mehta, Vladimir Guilmanov,
and Robert Nicolosi. US Patent Application
60/092,446 filed on |
Research Papers and
Reviews:-
(To see abstract of paper- click here)
1.
A Chemo-enzymatic Synthesis of Imperanene via
Enzymatic Assymertization of an Intermediary 1,3-diol. Jason Carr and Kirpal S. Bisht.
2.
Enantio Enriched Substituted Polycaprolactones
by Enzyme Catalysis. Kirpal S. Bisht,
3.
Intramolecular inclusion in novel octaester
cavitands. Eric Dueno and Kirpal S, Bisht. Chemical Communications,
954 – 955 (2004).
4.
Lipase-catalyzed resolution of racemic substituted b-Aryl- b-Lactams.
5.
Lipase catalyzed Regioselective transesterification
in peracylated sophorolipids catalyzed by Candida
6.
A MALDI, TGA, TG/MS, and DEA study of the irradiation effects on PMMA. S. R. Tatro, G. R. Baker, Kirpal S. Bisht
and J. P. Harmon. Polymer,
44, 167-176 (2003).
7.
Solventless enantioelective
ring-opening polymerization of substituted e-caprolactones by enzymatic catalysis. Talal
F. Al Azemi,
8.
One-step synthesis of polycarbonates bearing pendant functional groups by
ring-opening polymerization. Talal F. Al Azemi
and Kirpal S. Bisht. Journal of
Polymer Science-A: Polymer Chemistry. 40, 1267-1274 (2002).
9.
Lipase-catalyzed solvent-free kinetic resolution of substituted racemic e-caprolactones.
10.
Functional polycarbonates synthesis: Enzymatic approach. Talal F. Al-Azemi, and Kirpal S. Bisht. In Biocatalysis in Polymer Science, ACS,
11.
Synthesis of novel bis- and tris-(cyclic
carbonate)s and their use in preparation of polymer
networks. Talal F. Al Azemi and
Kirpal S. Bisht. POLYMER. 43,
2161-67 (2002).
12.
Novel poly(carbonate) and poly(carbonate-ester)
networks. Talal F. Al Azemi and
Kirpal S. Bisht. Polymer
Prep. 43(1), 613-614 (2002).
13.
Chiral polyesters by in-vitro enzymatic catalysis. Talal F. Al Azemi and Kirpal S. Bisht.
Polymer Prep.
43(1), 704-705 (2002).
14.
The synthesis and polymerization of glycolipid-based
monomers. Kirpal S. Bisht and Richard A. Gross. In ACS Symposium Series # 786 Biopolymers
from Polysaccharides and agroproteins. American Chemical Society,
15.
Synthesis of novel polycarbonates containing pendant carboxyl groups by enzyme
catalysis. Talal F. Al-Azemi, Kirpal S. Bisht. Polymeric Materials: Science and Engineering, 84, 1045-46 (2001).
16.
Enzyme-Catalyzed Ring-Opening Copolymerization of
5-Methyl-5-benzyloxycarbonyl-1,3-dioxan-2-one (MBC)
with Trimethylene carbonate (TMC): Synthesis and
Characterization. Talal F Al-Azemi, Julie P. Harmon and
Kirpal S. Bisht. Biomacromolecules, 1, 493-500 (2000).
17.
Glycolipids from Candida
bombicola: Polymerization of a 6-O-acryloyl sophorolipid derivative. Kirpal S. Bisht, Wei Gao
and Richard A. Gross. Macromolecules,
33, 6208-6210 (2000).
18.
Functional polycarbonate synthesis: Enzymatic approach. Kirpal
S. Bisht and Talal F. Al Azemi. Proc. Am. Chem. Soc.: Polymer Preprints,
41, 1865-66 (2000).
19. Novel Functional Polycarbonate by
Lipase-Catalyzed Ring-Opening Polymerization of 5-Methyl-5-benzyloxycarbonyl-1,
3-dioxan-2-one. Talal F. Al Azemi and Kirpal S. Bisht.
Macromolecules, 32,
6536-6540 (1999).
20.
Chemoenzymatic Synthesis of a Multiarm
Poly(lactide-co-e-caprolactone). Fang
Deng, Kirpal S. Bisht, Richard A. Gross, and David L. Kaplan. Macromolecules, 32,
5159-5161 (1999).
21.
Constituents of the yew trees.
22.
Enzyme-mediated regioselective acylations
of sophorolipids. Kirpal S. Bisht, Richard A. Gross, and
David L. Kaplan. Journal
of Organic Chemistry, 64, 780-789 (1999).
23.
Enzymatic polymerization of poly (e-CL)
containing an ethyl glucopyranoside head group: an
NMR study. Kirpal S. Bisht, Richard A. Gross, and Ashok L.
Cholli. Applied
Spectroscopy, 52, 1472-1478 (1998).
24.
Ethyl glucoside as a multifunctional initiator for
enzyme-catalyzed regioselective lactone
ring-opening polymerization. Kirpal S. Bisht, Fang Deng,
Richard A. Gross, David L. Kaplan, and Graham Swift. Journal of the American Chemical Society,
120, 1363-1367 (1998).
25.
Monomer and Polymer Synthesis by Lipase-catalyzed Ring-Opening Reactions.
Kirpal S. Bisht, Lori A. Henderson, Yuri Y. Sivirkin,
Richard A. Gross, David L. Kaplan and Graham Swift. In ACS
Symposium Series 684 Enzymes in Polymer
Synthesis. American Chemical Society,
26.
Novel enzymatic de-esterification studies on
substituted polyacetoxybenzamides. VS Parmar, A Kumar, AK Prasad, R
27.
Synthesis and anti-invasive activity of novel 1,3 –diarylpropenones. Parmar VS, Jain SC, Bisht KS, Sharma NK, Himanshu, Gupta S.
Indian Journal of Chemistry Section B, 37, 628-643 (1998).
28.
Lipase-catalysed selective deacetylation
of phenolic/enolic acetoxy
groups in peracetylated benzyl phenyl ketones. Parmar VS, Pati HN, Azim A, Kumar R, Himanshu, Bisht KS, Prasad AK, Errington
W. Bioorganic & Medicinal Chemistry,
6, 109-118 (1998).
29.
Chemical Constituent of Taxus canadensis.
Carl E. Olsen, R Singh, Suman Gupta, Kirpal S. Bisht,
Sanjay Malhotra, Rajni Jain,
Subhash C. Jain, and Virender
S. Parmar. Indian
Journal of Chemistry, Sec. B, 37, 828-831 (1998).
30.
Utility of a novel lipase from Aspergillus terreus in deacetylation
reactions. Virender S. Parmar, Hari N. Pati, Raman P. Yadav, Ajay Kumar, Kirpal S.
Bisht, R Gupta, S Davidson, Poonam, R. K. Sexena. Biocatalysis Biotransformations,
16, 17-25 (1998).
31.
Glycolipid containing polyacrylate
and polyacrylamide copolymers. Kirpal
S. Bisht, Arthur C. Waterson, and Richard A. Gross.
Proc. Am. Chem. Soc.: PMSE, 78,
246-247 (1998).
32.
Chemoenzymatic synthesis of a multiarm
poly(lactide-co-e-caprolactone). Fang
Deng, Kirpal S. Bisht, Richard A. Gross, David L. Kaplan, and Graham Swift.
Proc. Am. Chem. Soc.: Polymer Preprints,
39, 78-79 (1998).
33.
Bioactivity of extracellular glycolipids
- investigation of potential anti-cancer activity of sophorolipids and sophorolipid-derivatives Scholz,
C.; Mehta, S.; Bisht K.; Guilmanov, V.; laplan, D.; Nicolosi, R. and
Gross, R. Proc. Am. Chem. Soc.: Polymer
Preprints, 39, 168-169 (1998).
34.
Lipase-catalyzed ring-opening polymerization of Trimethylene
carbonate. Kirpal S. Bisht, Yuri Y. Sivirkin, Lori A.
Henderson, Richard A. Gross, David L. Kaplan and Graham Swift. Macromolecules, 30,
7735-7742 (1997).
35.
Enzyme-catalyzed Ring-Opening polymerization of w-Pentadecalactone. Kirpal S. Bisht, Lori
A. Henderson, Richard A. Gross, David L. Kaplan, and Graham Swift. Macromolecules, 30,
2705-2711 (1997).
36.
Novel chemoselective deesterification
of esters of polyacetoxy aromatic acids by lipases.
VS Parmar, A Kumar, KS Bisht, S Mukherjee, AK Prasad, SK Sharma, J. Wengel and CE Olsen. Tetrahedron, 53, 2163-2176 (1997).
37.
Phytochemistry of the genus Piper. Parmar VS, Jain SC, Bisht KS, Jain R, Taneja
P, Jha A, Tyagi OD, Prasad
AK, Wengel J, Olsen CE, Boll PM. Phytochemistry, 46, 597-673 (1997).
38.
Anti-invasive activity of alkaloids and polyphenolics
in vitro. Parmar VS, Bracke ME, Philippe J, Wengel J, Jain SC, Olsen CE, Bisht KS, Sharma NK, Courtens A, Sharma SK, Vennekens
K, VanMarck V, Singh SK, Kumar N, Kumar A, Malhotra S, Kumar R, Rajwanshi VK, Jain R, Mareel MM. Bioorganic
& Medicinal Chemistry, 5, 1609-1619 (1997).
39.
Lipase-catalyzed ring-opening polymerization of cyclic carbonates. Kirpal S. Bisht, Yuri Y. Sivirkin, Richard
A. Gross, David L. Kaplan and Graham Swift. Proc. Am. Chem. Soc.: PMSE, 76, 421-422 (1997).
40.
Chiral discrimination by hydrolytic enzymes in
synthesis of optically pure materials. VS
41.
Hydrolytic reactions on polyphenolic perpropanoates by porcine pancreatic lipase immobilized in microemulsion-based gels. Parmar VS, Pati HN, Sharma
SK, Singh A, Malhotra S, Kumar A, Bisht KS. Bioorganic
& Medicinal Chemistry Letters,
6, 2269-2274 (1996).
42.
Chemoprevention of carcinogen-DNA binding: The relative role of different
oxygenated substituents on 4-methylcoumarins in the
inhibition of aflatoxin B-1-DNA binding in vitro. Raj
HG, Gupta S, Biswas G, Singh S, Singh A, Jha A, Bisht
KS, Sharma SK, Jain SC, Parmar VS. Bioorganic & Medicinal Chemistry 4, 2225-2228 (1996).
43.
Novel biotransformations on peracylated
polyphenolics by lipases immobilized in microemulsion-based gels and on carbohydrates by Candida
44.
Synthesis and X-ray structure of 2-(3-methyl-2-butenyl)-3,4,5-trimethoxyphenol:
apotent anti-invasive agent against solid tumours. VS Parmar, S Gupta, KS Bisht, S
Mukherjee, PM Boll and W Errington. Acta Chemica Scandinavica, 50, 558-560 (1996)
45.
3,5-Dichloro-2,6-dimethoxycyclohexa-2,5-diene-1,4-dione.
S Mukherjee, KS Bisht, VS Parmar and W Errington.
Acta Crystallographica,
52C, 1211-1213 (1996).
46.
Synthesis, antimicrobial and antiviral activities of novel polyphenolic compounds. VS Parmar, KS Bisht, R Jain,
S Singh, SK Sharma, S Gupta, OD tyagi, A Vardhan, HN Pati, DV Berghe and
AJ Vlietinck. Indian Journal of Chenistry, 35B, 220-232 (1996).
47.
Neolignans, cyclohexanes
and alkaloids from Piper wightii. PM Boll, AK Prasad, OD Tyagi, J Wengel, CE Olsen, N
Kumar, KS Bisht and VS Parmar. Recueil des Travaux Chimiques des Pays-Bas (Journal of the Royal
Netherlands Chemical Society), 115, 9-12 (1996).
48.
Schiff bases of amino acids as new substrates for the enantioselective
enzymatic hydrolysis and accompanied asymmetric transformations in aqueous
organic solvents. VS Parmar, A Singh, KS Bisht, N Kumar, YN Belokon,
KA Kochetkov, NS Ikonnikov,
SA Orlova, VI Tararov and
TF Saveleva. Journal of Organic Chemistry, 61, 1223-1227 (1996).
49.
Preparative and mechanistic aspects of interesterification
reactions on diols and peracetylated
polyphenolic compounds catalyzed by porcine
pancreatic lipase. KS Bisht, A Kumar, N Kumar and VS
Parmar. Pure and
Applied Chemistry, 68, 749-752 (1996).
50.
Enzymes in organic media as catalysts for polyester synthesis. RA Gross, J Xu, YY Sivirkin, LA Henderson, KS
Bisht, DL Kaplan and G Swift. Proc. Am.
Chem. Soc.: PMSE, 74, 67-68 (1996).
51.
3-[3-(4-Bromophenyl)-1-phenylpyrazol-5-yl]-2H-1-benzopyran-2-one. Sanjay K. Singh,
52.
5-Cyanomethyl-3-(4-methylphenyl)-1-phenylpyrazole. Sanjay K.
Singh, Ajay Kumar, Archana Vats, Kirpal S.Bisht,
53.
Synthetic and mass spetral studies on new 1,3-diphenylpro-2-eneones of agrochemical interest. VS
54.
Methylenedioxyphenyl substituted compounds from Piper species as inhibitors of liver microsomes-mediated aflatoxin
B1-DNA binding in vitro. HG Raj, S Gupta, AK Prasad, PM Boll, J Wengel, G Biswas, SK Singh, NK Sharma, KS Bisht and VS
Parmar. Bioorganic and
Medicinal Chemistry Letters, 5, 1567-1572 (1995).
55.
Neolignans and a lignan
from Piper clarkii.
AK Prasad, OD Tyagi, J Wengel,
PM Boll, CE Olsen, KS Bisht, A Singh, A Sarangi, R
Kumar, SC Jain and VS Parmar. Phytochemistry, 38, 655-658 (1995).
56.
(Z)-Ethyl 2-cyano-3-methylsulfinyl-3-thiomethylpropenoate. SK Singh,
57. A benzoic acid ester from
Uvaria narum. VS Parmar, KS Bisht, A Malhotra,
A Jha, W Errington, OW Howarth, OD Tyagi, PC Stein, S
Jensen, PM Boll and CE Olsen. Phytochemistry, 38, 951-955 (1995).
58.
Neolignan from Piper
schmidtii and reassignment of the structure of schmiditin. OD Tyagi, AK Prasad,
J Wengel, PM Boll, CE Olsen, VS Parmar, NK Sharma, A Jha and KS Bisht. Acta Chemica Scandinavica, 49,
142-148 (1995).
59.
Potentially useful lipase-catalyzed transesterifications.
AK
60.
Isothionate in certain red algae. PB Holst, SE Nielsen, U Anthoni, KS
Bisht, C Christophersen, S Gupta, VS Parmar, PH
Nielsen, DB Sahoo and A Singh. Journal of Applied Phycology, 6, 443-446 (1994).
61.
Benzofuranoid neolignans
from Piper wightii
Miq. OD Tyagi, J Wengel, AK Prasad, PM Boll, CE Olsen, HN Pati, KS Bisht and
VS Parmar. Acta Chemica Scandinavica,
48, 1007-1011 (1994).
62.
Biotransformations in the regioselective
deacetylation of phenolic peracetates in organic solvents. KS
Bisht, OD Tyagi, AK Prasad, NK Sharma, S Gupta and VS
Parmar. Bioorganic
and Medicinal Chemistry, 2, 1015-1020 (1994).
Errata: 3: (7) 997-997 JUL 1995.
63.
Neolignans and an isoprenylated
phenol from Piper clarkii.
S Jensen, CE Olsen, OD Tyagi, PM Boll, FA Hussaini, S Gupta, KS Bisht and VS Parmar. Phytochemistry, 36, 789-792 (1994).
64.
Novel constituents of Uvaria
species. VS Parmar, OD Tyagi, A
Malhotra, SK Singh, KS Bisht and R Jain. Natural Product Reports,
11, 219-224 (1994).
65.
Synthesis, biological activity and solvent-induced shifts in the 1H NMR spectra
of 2,3-dihydro-4H-benzopyran-4-ones. VS Parmar, A Vardhan, SK Sharma, NK Sharma
and KS Bisht. Indian
Journal of Chemistry, 33B, 17-26 (1994).
66.
Lignans and neolignans from
stems of Piper wightii.
AK Prasad, OD Tyagi, J Wengel,
PM Boll, CE Olsen, S Gupta, NK Sharma, KS Bisht and VS Parmar. Tetrahedron, 50,
10579-10586 (1994).
67.
Highly oxygenated bioactive flavones from Tamarix. VS
68.
Lignans and neolignans from
stems and fruits of Piper wightii. AK Prasad, OD Tyagi,
J Wengel, PM Boll, CE Olsen, NK Sharma, KS Bisht, S
Gupta and VS Parmar. Tetrahedron,
50, 2231-2240 (1994); Corrigendum Tetrahedron, 50, 6721 (1994).
69.
A rare biflavone from Taxus baccata. VS Parmar, A
Vardhan, KS Bisht, NK Sharma, R Jain, P Taneja, OD Tyagi and PM Boll. Indian Journal of Chemistry,
32B, 601-603 (1993).
70.
Regioselective enzyme-catalyzed deacetylation
of benzyl phenyl ketone peracetates
in organic solvents. VS
71.
Diastereo- and enantioselective
esterification of butane 2,3-diol
catalyzed by the lipase from Pseudomonas flourescens. KS Bisht, VS Parmar and
DHG Crout. Tetrahedron:
Asymmetry, 4, 957-958 (1993).
72.
Regioselective esterification
of diols and triols with
lipases in organic solvents. VS Parmar, R
73.
Lignans and neolignans from
Piper schmidtii.
OD Tyagi, S Jensen, PM Boll, NK
74.
Lipase-catalysed selective deacylation
of peracetylated benzopyranones.
VS
75.
Regioselective hydrolysis of polyacetoxy
aromatic ketones with lipases in organic solvents. VS
Parmar, C
76.
Potential applications of enzyme-mediated transesterifications
in the synthesis of bioactive compounds. VS Parmar, AK Prasad, NK
Sharma, KS Bisht, R Sinha and P Taneja. Pure and Applied Chemistry, 64, 1135-1139 (1992).
77.
A wax ester from Piper clarkii. PM Boll, M Hald, VS Parmar, OD